Description

Enkephalin, Ala(2)-Val(5)- is a synthetic peptide analog of the endogenous opioid peptide enkephalin, specifically modified at the second and fifth amino acid positions. This modification is designed to enhance its metabolic stability and receptor selectivity, making it a valuable tool for advanced neuroscience and pharmacological research. It is essential for researchers and developers in the pharmaceutical and biotechnology sectors who are investigating pain pathways, neuropsychiatric disorders, and novel therapeutic agents targeting the opioid receptor system.

Application

• Neuroscience Research: Used as a selective ligand in receptor binding assays and functional studies to elucidate the role of δ-opioid receptors.
• Drug Discovery: Serves as a reference standard and lead compound in the development of new analgesics with improved side-effect profiles.
• Biochemical Studies: Employed in enzymatic stability assays to study peptide metabolism and design degradation-resistant analogs.
• Cell Signaling Pathways: Applied in vitro to investigate intracellular signaling cascades activated by opioid receptor engagement.
• Academic & Institutional Research: A key reagent for universities and research institutes studying neuropharmacology and peptide biochemistry.

Basic Information

Product Name	Enkephalin, Ala(2)-Val(5)-
CAS No.	78859-44-6
Molecular Formula	C27H41N7O7
Molecular Weight	575.66 g/mol
Synonyms	[Ala2, Val5]-Enkephalin; H-Tyr-Ala-Gly-Phe-Val-OH; δ-Selective Enkephalin Analog; DADLE Analog; (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenyl-N-[(2S)-1-hydroxy-3-methyl-1-oxobutan-2-yl]propanamide
EINECS	Contact for details

Quality Control

Our Enkephalin, Ala(2)-Val(5)- is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for peptide synthesis, and custom purity grades or specific analytical testing can be accommodated upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95%
Single Impurity (HPLC)	≤1.0%
Water Content (KF)	≤5.0%
Peptide Content	≥80%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.