Description

Enkephalin-Met, Arg(6)-Phenh2(7)- CAS NO 78761-61-2 is a synthetic peptide analog of the endogenous opioid peptide [Met]-enkephalin, modified with an arginine substitution at position 6 and a phenylalanine derivative at position 7. This compound is of significant interest for its potential role in modulating opioid receptor activity and related neurological pathways. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for advanced neurobiological studies, drug discovery, and the development of novel therapeutic agents targeting pain management and neurological disorders.

Application

• Neuroscience Research: As a key tool for investigating the structure-activity relationships (SAR) of opioid peptides and their interactions with delta (δ) and mu (μ) opioid receptors.
• Drug Discovery Programs: Serving as a lead compound or reference standard in the development of new analgesics with potentially improved efficacy or reduced side-effect profiles.
• Biochemical Assays: Used in competitive binding assays, receptor activation studies, and other in vitro tests to screen for new opioid ligands.
• Academic & Institutional Studies: Fundamental research into endogenous pain modulation, neurotransmitter systems, and peptide biochemistry.
• Peptide Chemistry & Synthesis: As an intermediate or reference material for the synthesis of more complex peptide libraries or novel analogs.
• Preclinical Development: Evaluation of pharmacokinetics, metabolic stability, and blood-brain barrier penetration for potential therapeutic candidates.

Basic Information

Product Name	Enkephalin-Met, Arg(6)-Phenh2(7)- CAS NO 78761-61-2
CAS No.	78761-61-2
Molecular Formula	C37H52N10O8S
Molecular Weight	796.94 g/mol
Synonyms	[Arg6, Phe(4-NH2)7]-Met-Enkephalin; H-Tyr-Gly-Gly-Phe-Met-Arg-Phe(4-NH2)-OH; [Met5, Arg6, Phe(4-NH2)7]-Enkephalin; Arg6-Phe(4-NH2)7-Met-Enkephalin; Opioid Peptide Analog; DALDA analog; Synthetic Enkephalin Derivative
EINECS	Contact for details

Quality Control

Our peptide products are manufactured and controlled under a strict quality management system. Each batch of Enkephalin-Met, Arg(6)-Phenh2(7)- undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing results from HPLC, MS, and amino acid analysis. Our quality commitment aligns with the standards expected for research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dimethyl sulfoxide (DMSO), acetic acid solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.