Description

(R)-(+)-n-[1-(1-Naphthyl)Ethyl]Succinamic Acid CAS NO 78681-09-1 is a high-purity chiral building block and resolving agent of significant importance in asymmetric synthesis. Its value lies in its ability to facilitate the separation and purification of enantiomers, which is critical for developing single-isomer pharmaceuticals and advanced materials. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for process development and the production of optically active intermediates.

Application

• Chiral Resolution Agent: Used for the separation of racemic mixtures of acids, amines, and alcohols via diastereomeric salt formation.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis Catalyst/ Ligand Precursor: Employed in the development of chiral catalysts and auxiliaries for stereoselective reactions.
• Agrochemical Research: Used in the synthesis of chiral herbicides, fungicides, and pesticides where specific stereochemistry is required for bioactivity.
• Analytical Chemistry Standard: Acts as a reference standard for HPLC and other chromatographic methods to determine enantiomeric purity.
• Fine Chemical Synthesis: Utilized in academic and industrial R&D for constructing complex molecules with defined stereocenters.

Basic Information

Product Name	(R)-(+)-n-[1-(1-Naphthyl)Ethyl]Succinamic Acid
CAS No.	78681-09-1
Molecular Formula	C₁₇H₁₉NO₃
Molecular Weight	285.34 g/mol
Synonyms	(R)-(+)-1-(1-Naphthyl)ethylammonium hydrogen succinate; (R)-N-(1-(Naphthalen-1-yl)ethyl)succinamic acid; (R)-1-(1-Naphthyl)ethylsuccinamic acid; (R)-NEES; (R)-(+)-NEES acid; (R)-1-(1-Naphthyl)ethylammonium succinate; (R)-α-Methyl-1-naphthaleneethylamine succinamic acid; (R)-1-(1-Naphthyl)ethylamine succinamic acid
EINECS	Contact for details

Quality Control

Our (R)-(+)-n-[1-(1-Naphthyl)Ethyl]Succinamic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, consistent with research and process development grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.