Description

Iomeprol is a non-ionic, water-soluble, iodinated contrast agent belonging to the class of triiodinated benzoic acid derivatives. Its primary value lies in its excellent safety and tolerability profile, providing high-quality radiographic imaging with low osmolality and viscosity. This makes it a critical component for diagnostic imaging procedures in hospitals and specialized clinics worldwide. Professionals in the pharmaceutical manufacturing and diagnostic imaging sectors rely on high-purity Iomeprol for formulating safe and effective injectable contrast media.

Application

• X-ray Contrast Media: Primary use as an active pharmaceutical ingredient (API) in injectable formulations for enhanced visualization in computed tomography (CT) scans.
• Angiography and Arteriography: Used for imaging blood vessels, including coronary, cerebral, and peripheral arteries, to diagnose blockages or aneurysms.
• Urography: Employed in procedures to examine the urinary tract, including the kidneys, ureters, and bladder.
• Myelography: Facilitates imaging of the spinal canal and the subarachnoid space surrounding the spinal cord.
• Arthrography: Used for joint imaging to assess cartilage, ligaments, and joint capsules.
• Pharmaceutical Intermediates: Serves as a key synthetic intermediate in the research and development of other iodinated contrast agents or related diagnostic compounds.

Basic Information

Item	Detail
Product Name	Iomeprol
CAS No.	78649-41-9
Molecular Formula	C24H36I3N3O9
Molecular Weight	777.18 g/mol
Synonyms	Iomeprolum; Iomeron; 5-[3-Hydroxy-2-(hydroxymethyl)propylcarbamoyl]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide; Iopamiron 300; Iomeprolo; Iomeprol (USAN); Iomeprolum (INN-Latin); Ioversol related compound A
EINECS	Contact for details

Quality Control

Our Iomeprol is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications, including specifications for assay, related substances, residual solvents, and heavy metals. A comprehensive Certificate of Analysis (COA) is provided with each batch, documenting compliance with in-house specifications aligned with major pharmacopoeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 5.0 %
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Iodine Content	48.0% - 50.0%
pH (5% Solution)	6.5 - 7.5
Bacterial Endotoxins	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.