Description

2-Ethoxy-1-Fluoronaphthalene is a specialized fluorinated naphthalene derivative, serving as a high-value intermediate in advanced organic synthesis. Its core value lies in the strategic combination of an ethoxy group and a fluorine atom on the naphthalene scaffold, enabling precise molecular modifications. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of fluorinated organic semiconductors and liquid crystal compounds for electronic displays.
• Fluorine Chemistry Research: A valuable substrate for studying nucleophilic aromatic substitution (SNAr) reactions and developing new fluorination methodologies.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.
• Polymer Modification: Acts as a functional monomer or additive to introduce fluorine-containing groups into polymer chains, altering surface properties and stability.

Basic Information

Product Name	2-Ethoxy-1-Fluoronaphthalene
CAS No.	78649-26-0
Molecular Formula	C₁₂H₁₁FO
Molecular Weight	190.21 g/mol
Synonyms	1-Fluoro-2-ethoxynaphthalene; 2-Ethoxy-1-fluoronaphthalene; 1-Fluoro-2-naphthol ethyl ether; Naphthalene, 1-fluoro-2-ethoxy-; 78649-26-0; 2-Ethoxy-1-fluoronaphthalene; 1-Fluoro-2-ethoxynaphthalene
EINECS	Contact for details

Quality Control

Our 2-Ethoxy-1-Fluoronaphthalene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to reliable supply and traceability supports your R&D and scale-up processes with confidence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.