Description

n-(Methylsulfonyl)-n-Phenylglycine CAS NO 78581-20-1 is a specialized sulfonamide derivative of glycine, serving as a high-value synthetic intermediate in advanced organic synthesis. Its unique structure, featuring both a phenylglycine backbone and a methylsulfonyl group, makes it a critical building block for constructing complex molecules with targeted biological or material properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or requiring specific sulfonamide pharmacophores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators where the phenylglycine-sulfone moiety can impart unique activity.
• Peptidomimetics & Bioactive Molecule Synthesis: Serves as a non-natural amino acid analog for creating modified peptides and constrained scaffolds in medicinal chemistry.
• Ligand & Catalyst Development: Employed in organometallic chemistry and catalysis research for constructing specialized chelating ligands.
• Material Science Precursor: Potential building block for advanced polymers or functional materials requiring specific sulfone linkages.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	n-(Methylsulfonyl)-n-Phenylglycine
CAS No.	78581-20-1
Molecular Formula	C9H11NO4S
Molecular Weight	229.25 g/mol
Synonyms	N-(Phenyl)-N-(methylsulfonyl)glycine; (Methylsulfonyl)(phenyl)aminoacetic Acid; N-Phenyl-N-(methylsulfonyl)glycine; Glycine, N-(methylsulfonyl)-N-phenyl-; NSC 339586; Benzenesulfonamide, N-(carboxymethyl)-N-methyl-; (Methanesulfonyl)(phenyl)aminoacetic Acid
EINECS	Contact for details

Quality Control

Our n-(Methylsulfonyl)-n-Phenylglycine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.