Description

(Cyano-Phenyl-Methyl)-Carbamic Acid tert-Butyl Ester is a high-value, protected amino acid derivative used as a critical building block in organic synthesis. This compound matters for its role as a versatile intermediate in the production of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing peptide mimetics and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting protease inhibition or containing modified amino acid backbones.
• Peptidomimetic Research: Serves as a protected α-amino nitrile derivative for constructing non-peptide scaffolds that mimic peptide structure and function.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific chiral centers are required for biological activity.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring specialized amino acid derivatives.
• Academic Research: A valuable reagent in university and institutional labs for methodological development in asymmetric synthesis and heterocyclic chemistry.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for the amine functionality in multi-step synthetic sequences.

Basic Information

Item	Details
Product Name	(Cyano-Phenyl-Methyl)-Carbamic Acid tert-Butyl Ester
CAS No.	78558-73-3
Molecular Formula	C13H16N2O2
Molecular Weight	232.28 g/mol
Synonyms	Boc-α-Amino-α-phenylacetonitrile; N-(tert-Butoxycarbonyl)-α-amino-α-phenylacetonitrile; tert-Butyl (cyano(phenyl)methyl)carbamate; 2-((tert-Butoxycarbonyl)amino)-2-phenylacetonitrile; Boc-Amino(phenyl)acetonitrile; N-Boc-α-phenylglycinonitrile; (α-Cyano)benzylcarbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our (Cyano-Phenyl-Methyl)-Carbamic Acid tert-Butyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of advanced synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment. We support compliance with relevant guidelines for use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.