Description

Acetamide, 2,2,2-Trifluoro-n-(Phenylsulfonyl)- is a specialized fluorinated sulfonamide derivative that serves as a high-value synthetic intermediate. Its unique molecular structure, featuring both a trifluoroacetamide and a phenylsulfonyl group, makes it a critical building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for advanced synthesis projects, including the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those requiring sulfonamide or trifluoromethyl motifs for enhanced bioactivity and metabolic stability.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the fluorine atoms can improve compound lipophilicity and target binding.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and coatings with specific chemical resistance or surface properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocycles and other sophisticated organic frameworks.
• Ligand and Catalyst Development: Potential use in designing novel ligands for catalytic systems or metal-organic frameworks (MOFs).

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-(Phenylsulfonyl)-
CAS No.	78542-75-3
Molecular Formula	C8H6F3NO3S
Molecular Weight	253.20 g/mol
Synonyms	N-(Phenylsulfonyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(phenylsulfonyl)acetamide; Benzenesulfonamide, N-(trifluoroacetyl)-; N-(Trifluoroacetyl)benzenesulfonamide; Trifluoroacetylsulfanilamide; TFASA; Phenylsulfonyl trifluoroacetamide; α,α,α-Trifluoro-N-(phenylsulfonyl)acetamide
EINECS	Contact for details

Quality Control

Our Acetamide, 2,2,2-Trifluoro-n-(Phenylsulfonyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), impurity profiles, and physical characteristics. Our quality commitment supports applications requiring high-purity intermediates for regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.