Description

Lhrh, n-ε-Azidobenzoyl-Lys(6)- CAS NO 78527-81-8 is a chemically modified peptide derivative, specifically a lysine-modified analog of Luteinizing Hormone-Releasing Hormone (LHRH). This compound is engineered for advanced biochemical research and development, offering a reactive azido group for site-specific conjugation via click chemistry. It is primarily utilized by pharmaceutical researchers, bioconjugation specialists, and diagnostic developers working on targeted drug delivery systems, novel therapeutic conjugates, and sophisticated molecular probes. The product's design enables precise and stable linkage to various biomolecules and surfaces, making it a critical tool for innovation in life sciences.

Application

• Bioconjugation & Click Chemistry: Serves as a key intermediate for the site-specific labeling and cross-linking of peptides, proteins, antibodies, and other biomolecules using copper-catalyzed or strain-promoted azide-alkyne cycloaddition (SPAAC).
• Targeted Drug Delivery Systems: Used in the research and development of LHRH receptor-targeted therapeutics, where the peptide moiety directs cytotoxic agents or imaging probes specifically to cancer cells.
• Diagnostic Probe Development: Facilitates the creation of advanced molecular imaging agents and in vitro diagnostic (IVD) reagents for research and clinical applications.
• Pharmaceutical R&D: Acts as a critical building block in the synthesis of novel peptide-drug conjugates (PDCs) and other next-generation biopharmaceuticals.
• Material Science & Surface Functionalization: Enables the modification of nanoparticles, polymers, and solid supports with bioactive peptides for biosensor and tissue engineering applications.
• Academic & Industrial Research: Supports fundamental studies in endocrinology, receptor biology, and chemical biology as a tool compound.

Basic Information

Product Name	Lhrh, n-ε-Azidobenzoyl-Lys(6)- CAS NO 78527-81-8
CAS No.	78527-81-8
Molecular Formula	C66H88N18O13
Molecular Weight	1293.5 g/mol
Synonyms	Azido-LHRH; LHRH Azide Derivative; Nε-Azidobenzoyl-Lys6-LHRH; Luteinizing Hormone-Releasing Hormone Azido Analog; Gonadorelin Azide Derivative; Pyro-Glu-His-Trp-Ser-Tyr-AzBz-Lys-Leu-Arg-Pro-Gly-NH2; Click Chemistry LHRH Peptide; Azido-Peptide Conjugation Reagent
EINECS	Contact for details

Quality Control

Our Lhrh, n-ε-Azidobenzoyl-Lys(6)- is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency for research and development purposes. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and MS (Mass Spectrometry) for identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical parameters such as assay purity, related substances, and residual solvents. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere. Keep container tightly sealed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.