Description

3-(4-Fluorophenyl)Cyclohexanone is a versatile fluorinated cyclic ketone building block, valued for its unique structural motif that combines a cyclohexanone ring with a fluorinated aromatic system. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, including potential central nervous system (CNS) agents and anti-inflammatory compounds.
• Agrochemical Research: Used as a precursor in developing novel herbicides and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Asymmetric Synthesis: The prochiral ketone functionality makes it a suitable substrate for chiral reduction or other transformations to create enantiomerically pure intermediates.
• Polymer Modification: Employed to introduce fluorinated phenyl groups into polymer backbones to alter physical properties like thermal stability and solubility.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorinated probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	3-(4-Fluorophenyl)Cyclohexanone
CAS No.	78494-26-5
Molecular Formula	C12H13FO
Molecular Weight	192.23 g/mol
Synonyms	3-(4-Fluorophenyl)cyclohexanone; 4-Fluorophenyl Cyclohexyl Ketone; 1-(4-Fluorophenyl)-3-cyclohexanone; 3-(p-Fluorophenyl)cyclohexanone; Cyclohexanone, 3-(4-fluorophenyl)-; 78494-26-5; 4-Fluorobenzenecyclohexanone
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)Cyclohexanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.