Description

Cefminoxsodium CAS NO 78345-56-9 is a semi-synthetic, broad-spectrum cephalosporin antibiotic belonging to the cephamycin class. It is valued for its enhanced stability against β-lactamases and potent activity against a wide range of Gram-positive and Gram-negative bacteria. This active pharmaceutical ingredient (API) is essential for pharmaceutical manufacturers developing injectable antibiotic formulations targeting serious infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in sterile injectable antibiotic preparations.
• Hospital-Acquired Infection Treatment: Formulated for combating severe infections, including intra-abdominal, urinary tract, and respiratory tract infections.
• Surgical Prophylaxis: Used in injectable forms to prevent post-operative infections.
• Bacterial Resistance Management: A key component in therapeutic regimens targeting β-lactamase-producing bacterial strains.
• Veterinary Pharmaceuticals: Potential application in advanced antibiotic treatments for livestock.
• Research & Development: Serves as a reference standard and starting material for novel antibiotic synthesis in pharmaceutical R&D.

Basic Information

Product Name	Cefminoxsodium
CAS No.	78345-56-9
Molecular Formula	C16H20N7NaO7S2
Molecular Weight	517.49 g/mol
Synonyms	Cefminox Sodium; Cefminox Na; 6R-[6α,7β(R*)]]-7-[[(Carboxy-4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt; (6R,7S)-7-[[(2R)-2-(4-Hydroxyphenyl)-2-(sodiooxycarbonyl)acetyl]amino]-7-methoxy-3-[(1-methyl-1H-tetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Meicelin; MT-141; Antibiotic MT-141
EINECS	Contact for details

Quality Control

Our Cefminoxsodium is manufactured under strict quality management systems, targeting compliance with ICH Q7 guidelines for active pharmaceutical ingredients. Every batch undergoes comprehensive analytical testing including HPLC for purity, identification by IR and NMR, and stringent control of related substances and residual solvents. Certificates of Analysis (COA) documenting full compliance with agreed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
pH (10% solution)	4.5 - 6.5
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.