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Racemic-2,2Bis(Diphenylphosphino)-1,1Binaphthyl CAS NO 78327-87-8


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CAS No.:78327-87-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Racemic-2,2Bis(Diphenylphosphino)-1,1Binaphthyl CAS NO 78327-87-8 is a high-purity, atropisomeric bidentate phosphine ligand essential for advanced catalytic processes. Its primary value lies in its ability to act as a versatile chiral or achiral scaffold in transition metal catalysis, enabling precise control over reaction stereochemistry and yield. This compound is critically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for developing and scaling up asymmetric synthesis, including hydrogenation and cross-coupling reactions.

Application

  • As a key ligand in asymmetric hydrogenation reactions for the synthesis of chiral pharmaceutical intermediates.
  • As a catalyst component in cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex organic molecules.
  • In homogeneous catalysis research for developing new synthetic methodologies.
  • For the preparation of transition metal complexes used in academic and industrial research.
  • As a chiral auxiliary or resolving agent in stereoselective synthesis.
  • In the development of advanced materials and organometallic compounds.

Basic Information

Product Name Racemic-2,2Bis(Diphenylphosphino)-1,1Binaphthyl
CAS No. 78327-87-8
Molecular Formula C44H32P2
Molecular Weight 622.67 g/mol
Synonyms (±)-BINAP; rac-BINAP; rac-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl; 1,1'-Binaphthalene-2,2'-diylbis[diphenylphosphine]; BINAP (racemic); 2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl (racemate); (±)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl
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Quality Control

Our Racemic-2,2Bis(Diphenylphosphino)-1,1Binaphthyl is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, chiral purity (racemic confirmation), and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥98.0%
Chiral Purity (HPLC) Racemic mixture (50:50 enantiomer ratio)
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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