Description

N,n-Diethyl-2-Iodoacetamide is a specialized halogenated acetamide derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile alkylating and functionalizing agent, enabling the introduction of an iodoacetamide moiety into complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of potential drug candidates, particularly for creating covalent enzyme inhibitors or antibody-drug conjugates (ADCs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that require specific halogenated side chains.
• Bioconjugation Chemistry: Employed for labeling proteins, peptides, and other biomolecules due to its reactivity with thiol groups, facilitating studies in biochemistry and diagnostics.
• Material Science: Serves as a monomer or cross-linking agent in the preparation of specialized polymers with unique thermal or mechanical properties.
• Organic Synthesis Building Block: Utilized in nucleophilic substitution reactions, cross-coupling reactions (e.g., Suzuki, Heck), and for constructing complex heterocyclic compounds.
• Chemical Biology Probes: Acts as a key component in creating activity-based probes for studying enzyme function and metabolic pathways.

Basic Information

Item	Details
Product Name	N,n-Diethyl-2-Iodoacetamide
CAS No.	78258-15-8
Molecular Formula	C6H12INO
Molecular Weight	241.07 g/mol
Synonyms	2-Iodo-N,N-diethylacetamide; Diethyl(iodoacet)amide; N,N-Diethyliodoacetamide; Iodoacetic Acid Diethylamide; Acetamide, N,N-diethyl-2-iodo-; α-Iodo-N,N-diethylacetamide
EINECS	Contact for details

Quality Control

Our N,n-Diethyl-2-Iodoacetamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.