Description

n-Nitrosospermidine is a specialized nitrosamine compound of significant interest in biochemical and pharmaceutical research. This chemical serves as a critical intermediate and reference standard for studying nitrosation processes, DNA alkylation, and carcinogenesis mechanisms. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories focused on oncology, toxicology, and metabolic pathway analysis.

Application

• Biochemical Research: Used as a reference standard and intermediate in studies of polyamine metabolism and nitrosamine biochemistry.
• Oncology Research: Employed in mechanistic studies of carcinogenesis, particularly related to DNA adduct formation and alkylating agents.
• Toxicology Studies: Serves as a model compound for investigating the metabolic activation and toxicological profiles of N-nitroso compounds.
• Pharmaceutical Development: Acts as a key synthetic intermediate or impurity standard in the development of novel therapeutic agents.
• Analytical Chemistry: Used to develop and validate analytical methods (e.g., HPLC, LC-MS) for the detection and quantification of nitrosamines in complex matrices.
• Academic Research: Fundamental studies in organic chemistry, reaction mechanisms, and the synthesis of polyamine derivatives.

Basic Information

Product Name	n-Nitrosospermidine
CAS No.	78249-62-4
Molecular Formula	C8H19N5O
Molecular Weight	201.27 g/mol
Synonyms	N-Nitrosospermidine; 1,4-Diamino-2-azabutane, N-nitroso-; N-(3-Aminopropyl)-N-nitroso-1,3-propanediamine; N-Nitroso-N-(3-aminopropyl)-1,3-propanediamine; N1-Nitroso-N4-(3-aminopropyl)-1,4-butanediamine; N-Nitrosated spermidine; Nitrosospermidine
EINECS	Contact for details

Quality Control

Our n-Nitrosospermidine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR) for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results for identity, purity, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature, the container should be opaque or stored in dark conditions. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 2.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.