Description

(S)-1-n-Boc-Piperidine-2-Carboxamide CAS NO 78058-41-0 is a high-purity, single-enantiomer chiral building block and pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules where stereochemical integrity is paramount, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily utilized in the research and development of active pharmaceutical ingredients (APIs), particularly in the fields of neurology and metabolic disease, serving the needs of pharmaceutical R&D laboratories and fine chemical synthesis facilities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel drug candidates, especially for neurological and metabolic disorders.
• Asymmetric Synthesis: Used as a building block in stereoselective synthesis to introduce the (S)-piperidine-2-carboxamide moiety into target molecules.
• Protease Inhibitor Research: Serves as a core structural component in the development of protease inhibitors due to its peptide-like backbone.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Custom Synthesis: A starting material for the contract manufacturing of specialized fine chemicals and advanced intermediates.
• Academic Research: Used in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(S)-1-n-Boc-Piperidine-2-Carboxamide
CAS No.	78058-41-0
Molecular Formula	C11H20N2O3
Molecular Weight	228.29 g/mol
Synonyms	(S)-1-(tert-Butoxycarbonyl)piperidine-2-carboxamide; (S)-1-Boc-piperidine-2-carboxylic acid amide; (S)-N-Boc-pipecolic acid amide; (S)-1-Boc-2-piperidinecarboxamide; (2S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]piperidine-2-carboxamide; tert-Butyl (2S)-2-carbamoylpiperidine-1-carboxylate; (S)-1-Boc-Pip-NH2
EINECS	Contact for details

Quality Control

Every batch of (S)-1-n-Boc-Piperidine-2-Carboxamide is produced under controlled conditions and undergoes rigorous analytical testing to ensure high chemical and chiral purity. Our quality assurance protocols are designed to meet the stringent requirements of pharmaceutical R&D and cGMP guidelines where applicable. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with each shipment to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.