Description

1-Benzylpiperidine-4-Acetonitrile is a versatile nitrile-functionalized piperidine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both a benzyl-protected amine and a reactive nitrile group, makes it a valuable building block for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new drug candidates, particularly within the fields of central nervous system (CNS) agents and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel piperidine-based drug candidates targeting neurological disorders.
• Chemical Research & Development: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Employed in the development of advanced crop protection agents and pesticides.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	1-Benzylpiperidine-4-Acetonitrile
CAS No.	78056-67-4
Molecular Formula	C15H20N2
Molecular Weight	228.34 g/mol
Synonyms	4-(Cyanomethyl)-1-benzylpiperidine; 1-Benzyl-4-(cyanomethyl)piperidine; 1-Benzyl-4-piperidineacetonitrile; Piperidine-4-acetonitrile, 1-benzyl-; α-(1-Benzyl-4-piperidinyl)acetonitrile; NSC 334365; 1-Benzylpiperidin-4-ylacetonitrile
EINECS	Contact for details

Quality Control

Our 1-Benzylpiperidine-4-Acetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography and spectroscopic methods, to meet exacting customer specifications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.