Description

3-Trifluoromethylbenzoyl-Dialanine-4-Nitroanilide is a specialized synthetic peptide derivative designed for advanced research and development applications. This compound serves as a critical building block or analytical standard in the development of novel enzyme inhibitors and diagnostic assays. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on protease and peptidase studies. The product's unique structure, incorporating a trifluoromethylbenzoyl group and a nitroanilide chromophore, makes it valuable for high-throughput screening and mechanistic enzymology.

Application

• Protease/Peptidase Research: Used as a chromogenic or fluorogenic substrate for studying the activity and kinetics of specific proteolytic enzymes.
• Drug Discovery: Acts as a key intermediate or reference compound in the development of new therapeutic agents targeting protease pathways.
• Biochemical Assay Development: Employed in the formulation of sensitive and specific assay kits for diagnostic or research purposes.
• Enzyme Inhibitor Screening: Serves as a standard substrate in high-throughput screens to identify and characterize potential enzyme inhibitors.
• Academic Research: Utilized in university and institutional labs for fundamental studies in biochemistry, enzymology, and medicinal chemistry.
• Quality Control: Functions as a reference standard for the quality assurance of related pharmaceutical ingredients or biochemical reagents.

Basic Information

Product Name	3-Trifluoromethylbenzoyl-Dialanine-4-Nitroanilide
CAS No.	78044-16-3
Molecular Formula	C21H20F3N5O6
Molecular Weight	495.41 g/mol
Synonyms	3-(Trifluoromethyl)benzoyl-Ala-Ala-pNA; Ala-Ala-4-Nitroanilide derivative with 3-Trifluoromethylbenzoic acid; N-(3-Trifluoromethylbenzoyl)-L-alanyl-L-alanine 4-nitroanilide; Bz-Ala-Ala-pNA (3-CF3 analog); Protease Substrate 78044-16-3; AAPA-pNA (3-Trifluoromethyl); TFMB-Ala-Ala-pNA
EINECS	Contact for details

Quality Control

Our 3-Trifluoromethylbenzoyl-Dialanine-4-Nitroanilide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, identity confirmation by IR and NMR spectroscopy, and precise determination of water content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research-grade specifications. Our commitment to quality assurance guarantees material consistency and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.