Description

3-Butyn-2-Ol, 4-Chloro-2-Cyclopropyl- is a specialized alkyne derivative featuring a cyclopropyl substituent, serving as a versatile and valuable building block in advanced organic synthesis. Its unique molecular architecture, combining a reactive terminal alkyne with halogen and cyclic alkyl groups, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropyl moiety is a common bioactive motif.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or mechanical properties.
• Chemical Biology Probes: Utilized in click chemistry applications (e.g., CuAAC reactions) to create labeled molecules for studying biological pathways.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing novel ligands used in asymmetric catalysis and transition metal complexes.
• Fine Chemical Production: Intermediate for the manufacture of complex fragrance compounds, dyes, and other high-value specialty chemicals.

Basic Information

Product Name	3-Butyn-2-Ol, 4-Chloro-2-Cyclopropyl-
CAS No.	77985-09-2
Molecular Formula	C7H9ClO
Molecular Weight	144.60 g/mol
Synonyms	4-Chloro-2-cyclopropyl-3-butyn-2-ol; 2-Cyclopropyl-4-chloro-3-butyn-2-ol; 3-Butyn-2-ol, 4-chloro-2-cyclopropyl-; 4-Chloro-2-cyclopropylbut-3-yn-2-ol
EINECS	Contact for details

Quality Control

Our production of 3-Butyn-2-Ol, 4-Chloro-2-Cyclopropyl- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to the reactive alkyne functionality, it is recommended to store under an inert atmosphere for long-term stability and to minimize potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.