Description

((1-(p-Fluorobenzyl)-2-Methyl-4-Nitro-1H-Imidazol-5-Yl)Thio)Acetonitrile is a specialized, high-purity chemical intermediate characterized by its unique imidazole-thioacetonitrile structure with a fluorobenzyl substituent. This compound is critical for advanced organic synthesis, offering a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its nitro-imidazole core for biological activity.
• Chemical Biology Probes: Acts as a precursor for creating labeled compounds or probes used in studying biological mechanisms.
• Material Science: Potential use in the synthesis of specialty polymers or ligands for catalytic systems.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical production for clients.

Basic Information

Item	Detail
Product Name	((1-(p-Fluorobenzyl)-2-Methyl-4-Nitro-1H-Imidazol-5-Yl)Thio)Acetonitrile
CAS No.	77952-80-8
Molecular Formula	C₁₃H₁₁FN₄O₂S
Molecular Weight	306.32 g/mol
Synonyms	1-(4-Fluorobenzyl)-2-methyl-4-nitro-1H-imidazole-5-thioacetonitrile; 5-[(Cyanomethyl)thio]-1-[(4-fluorophenyl)methyl]-2-methyl-4-nitro-1H-imidazole; p-Fluorobenzyl-2-methyl-4-nitroimidazole-5-thioacetonitrile; 77952-80-8; 1-(p-Fluorobenzyl)-2-methyl-4-nitroimidazole-5-ylthioacetonitrile; 4-Nitro-1-(4-fluorobenzyl)-2-methyl-1H-imidazole-5-thioacetonitrile
EINECS	Contact for details

Quality Control

Our production of ((1-(p-Fluorobenzyl)-2-Methyl-4-Nitro-1H-Imidazol-5-Yl)Thio)Acetonitrile adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.