Description

2(1H)-Naphthalenone, 1-Fluorooctahydro- (CAS NO 77881-39-1) is a specialized fluorinated organic compound belonging to the class of hydrogenated naphthalenone derivatives. This compound is valued for its unique structural motif, which combines a partially saturated naphthalene core with a strategically positioned fluorine atom, making it a versatile intermediate for advanced chemical synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical sectors for the construction of complex molecules, where the fluorine atom can impart desirable metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorinated structure can enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for methodologies like fluorination studies, hydrogenation reactions, and cyclization processes.
• Ligand and Catalyst Development: The rigid, functionalized structure makes it a candidate for developing chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	2(1H)-Naphthalenone, 1-Fluorooctahydro-
CAS No.	77881-39-1
Molecular Formula	C₁₀H₁₃FO
Molecular Weight	168.21 g/mol
Synonyms	1-Fluorooctahydro-2(1H)-naphthalenone; 1-Fluorooctahydro-2-naphthalenone; 1-Fluorodecahydro-2-naphthalenone; Octahydro-1-fluoro-2(1H)-naphthalenone; Fluorinated perhydronaphthalenone; 1-Fluoro-1,2,3,4,4a,5,6,7-octahydro-2-naphthalenone
EINECS	Contact for details

Quality Control

Our 2(1H)-Naphthalenone, 1-Fluorooctahydro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.