Description

n-Desmethyl Iomeprol is a key intermediate in the synthesis of iomeprol, a non-ionic, iodinated contrast agent widely used in diagnostic imaging. This compound matters for its critical role in ensuring the purity, efficacy, and safety of the final pharmaceutical product. It is primarily needed by manufacturers and research institutions in the pharmaceutical and fine chemical sectors engaged in the development and production of X-ray and CT scan contrast media.

Application

• Pharmaceutical Intermediate: Primary use as a crucial synthetic precursor in the manufacturing of the contrast agent Iomeprol.
• Contrast Media Research: Serves as a reference standard and building block in R&D for novel iodinated contrast agents and their metabolites.
• Metabolite Studies: Used in analytical and pharmacological studies to understand the metabolism and pharmacokinetics of Iomeprol.
• Quality Control: Employed as an analytical standard in HPLC and other chromatographic methods for impurity profiling and assay of Iomeprol batches.
• Chemical Synthesis: A versatile intermediate for further chemical modifications in organic and medicinal chemistry research.

Basic Information

Product Name	n-Desmethyl Iomeprol
CAS No.	77868-40-7
Molecular Formula	C20H28I3N3O8
Molecular Weight	779.07 g/mol
Synonyms	1-N-Desmethyl Iomeprol; Iomeprol Impurity C; Iomeprol EP Impurity C; Iomeprol Related Compound C; 5-[Acetyl(2-hydroxyethyl)amino]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide; 5-[Acetyl(2-hydroxyethyl)amino]-2,4,6-triiodoisophthalamic acid bis(2,3-dihydroxypropyl) ester; Iomeprol metabolite intermediate.
EINECS	Contact for details

Quality Control

Our n-Desmethyl Iomeprol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-grade standards suitable for pharmaceutical intermediate use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.