Description

Falipamil is a selective calcium channel blocker belonging to the benzazepine chemical class. This compound is of significant interest in pharmaceutical research and development for its potential cardiovascular applications. It serves as a crucial intermediate or active pharmaceutical ingredient (API) for researchers and manufacturers in the life sciences sector. Global procurement of this material demands a supplier committed to stringent quality control and reliable supply chain integrity.

Application

Falipamil CAS NO 77862-92-1 is utilized in various advanced research and manufacturing contexts, primarily within the pharmaceutical industry.

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel cardiovascular drug candidates.
• Active Pharmaceutical Ingredient (API) Research: Used in preclinical and clinical research studies investigating calcium channel modulation.
• Biochemical Research: Employed as a tool compound to study calcium ion (Ca²⁺) flux and related cellular signaling pathways.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing.
• Process Chemistry Development: Supports scale-up and optimization of synthetic routes for pharmaceutical manufacturing.

Basic Information

Product Name	Falipamil
CAS No.	77862-92-1
Molecular Formula	C20H26N2O3
Molecular Weight	342.44 g/mol
Synonyms	Falipamil; AQ-A 39; AQA 39; 2-[3,4-Dimethoxyphenyl)methyl]-5-[2-(3,4-dimethoxyphenyl)ethyl]amino]-2-isopropylvaleronitrile; (R*,S*)-(±)-2-[[3,4-Bis(methyloxy)phenyl]methyl]-5-[[2-[3,4-bis(methyloxy)phenyl]ethyl]amino]-2-(1-methylethyl)pentanenitrile
EINECS	Contact for details

Quality Control

Our Falipamil is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure it meets high-grade standards suitable for research and development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.