Description

β-Endorphin (6-31) is a specific, biologically active fragment of the endogenous opioid peptide β-endorphin, identified by CAS No. 77761-27-4. This high-purity peptide fragment is critical for research into pain modulation, stress response, and neuroendocrine signaling pathways. It is an essential tool for pharmaceutical R&D, academic neuroscience, and biotechnology laboratories focused on developing novel therapeutic agents and diagnostic assays.

Application

• Neuroscience Research: Used as a reference standard and active agent in studies of opioid receptor binding, signal transduction, and the physiological effects of endorphins.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the discovery and screening of new analgesics and neuroprotective drugs.
• Biochemical Assays: Employed in the development and validation of immunoassays (ELISA, RIA) and other analytical methods for detecting endorphin levels.
• Cell Culture Studies: Applied in vitro to investigate the effects of β-endorphin fragments on cellular processes, immune function, and hormone release.
• Academic & Clinical Research: Supports fundamental research into the role of endogenous opioids in addiction, mood disorders, and chronic pain conditions.

Basic Information

Product Name	β-Endorphin (6-31)
CAS No.	77761-27-4
Molecular Formula	C140H220N38O42S
Molecular Weight	3163.6 g/mol
Synonyms	β-Endorphin (6-31); β-Endorphin fragment 6-31; Human β-Endorphin (6-31); Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu; β-Lipotropin (61-91) fragment 6-31; Opioid peptide fragment
EINECS	Contact for details

Quality Control

Our β-Endorphin (6-31) is manufactured under stringent conditions to ensure the highest standards of purity and consistency. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to meet the exacting requirements of research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.