Description

n-(5,5-Dimethyl-2-Oxotetrahydro-3-Furyl)-2,2,2-Trifluoroacetamide is a high-purity, specialized organic compound featuring a unique furanone-derived structure coupled with a trifluoroacetamide group. This molecular architecture makes it a valuable advanced intermediate for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring the incorporation of a trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the specific stereochemistry and fluorine atoms can contribute to biological activity.
• Material Science Precursor: Serves as a monomer or specialty additive in the research of advanced polymers and functional materials.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex heterocyclic frameworks and exploring new chemical reactions.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the properties and reactivity of fluorinated amides and lactones.

Basic Information

Item	Detail
Product Name	n-(5,5-Dimethyl-2-Oxotetrahydro-3-Furyl)-2,2,2-Trifluoroacetamide
CAS No.	77694-20-3
Molecular Formula	C8H10F3NO3
Molecular Weight	225.17 g/mol
Synonyms	2,2,2-Trifluoro-N-(5,5-dimethyl-2-oxotetrahydrofuran-3-yl)acetamide; 3-(Trifluoroacetamido)-5,5-dimethyl-2-tetrahydrofuranone; 5,5-Dimethyl-3-(2,2,2-trifluoroacetamido)dihydrofuran-2(3H)-one; 77694-20-3; TFAA derivative of 3-amino-5,5-dimethyl-2-tetrahydrofuranone
EINECS	Contact for details

Quality Control

Our n-(5,5-Dimethyl-2-Oxotetrahydro-3-Furyl)-2,2,2-Trifluoroacetamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.