Description

1-Butanone, 4-(4-(8-Chloro-10,11-Dihydrodibenzo(B,F)Thiepin-10-Yl)-1-Piperazinyl)-1-(4-Fluorophenyl)-, Dihydrochloride, Hydrate is a high-purity, complex organic salt of significant interest in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate, enabling the development of novel therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the synthesis of specialized active pharmaceutical ingredients (APIs) and for analytical reference standards.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel psychotropic or neurological drug candidates.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in regulatory testing.
• Research & Development: Serves as a precursor in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the final or penultimate steps of API manufacturing for targeted therapies.
• Process Chemistry: Used in scale-up and optimization studies for commercial pharmaceutical production.

Basic Information

Product Name	1-Butanone, 4-(4-(8-Chloro-10,11-Dihydrodibenzo(B,F)Thiepin-10-Yl)-1-Piperazinyl)-1-(4-Fluorophenyl)-, Dihydrochloride, Hydrate
CAS No.	77603-02-2
Molecular Formula	C28H29ClFN2OS • 2HCl • xH2O
Molecular Weight	Contact for details
Synonyms	Zotepine Impurity; Zotepine Related Compound; 4-(4-(8-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-1-piperazinyl)-1-(4-fluorophenyl)-1-butanone dihydrochloride hydrate; FR-1314 Dihydrochloride Hydrate; 1-Butanone, 4-[4-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-1-piperazinyl]-1-(4-fluorophenyl)-, dihydrochloride, hydrate
EINECS	Contact for details

Quality Control

Our 1-Butanone, 4-(4-(8-Chloro-10,11-Dihydrodibenzo(B,F)Thiepin-10-Yl)-1-Piperazinyl)-1-(4-Fluorophenyl)-, Dihydrochloride, Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Long-term storage under inert atmosphere is recommended.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.