Description

(Z)-2-Chloro-4-Hydroxy-9-(3-Dimethylaminopropylidene)Thioxanthene Hydrogen Maleate is a high-purity pharmaceutical intermediate and active ingredient with a defined stereochemistry. This compound is critical for ensuring the efficacy and consistency of downstream pharmaceutical formulations. It is primarily required by research institutions and manufacturers in the pharmaceutical and life sciences sectors for the development and production of specialized therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of specific active pharmaceutical ingredients (APIs).
• Neurological Research: Used in preclinical and clinical research related to central nervous system (CNS) agents.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development.
• Process Development: Employed in scaling up and optimizing synthetic routes for complex organic molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for GMP production.

Basic Information

Product Name	(Z)-2-Chloro-4-Hydroxy-9-(3-Dimethylaminopropylidene)Thioxanthene Hydrogen Maleate
CAS No.	77602-72-3
Molecular Formula	C22H22ClNO5S
Molecular Weight	447.93 g/mol
Synonyms	Zuclopenthixol Maleate; Zuclopenthixol Hydrogen Maleate; (Z)-Clopenthixol Maleate; (Z)-2-Chloro-4-(3-dimethylaminopropylidene)-9-hydroxy-2-thiafluorene Maleate; NSC 339024; Cis(Z)-Clopenthixol Maleate; (Z)-Clopenthixol Acid Maleate
EINECS	Contact for details

Quality Control

Our (Z)-2-Chloro-4-Hydroxy-9-(3-Dimethylaminopropylidene)Thioxanthene Hydrogen Maleate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and conformity to client specifications. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific regulatory or internal quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.