Description

2-Bromo-n-Cyclopropyl-Acetamide is a specialized brominated acetamide derivative featuring a cyclopropyl ring, serving as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its core value proposition lies in enabling the efficient construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity building block is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific functional groups or create constrained ring systems.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those requiring cyclopropane motifs for metabolic stability or conformational restriction.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the cyclopropyl group can enhance biological activity.
• Chemical Biology & Proteomics: Acts as a reactive handle for the selective modification of proteins or the synthesis of activity-based probes (ABPs) due to the electrophilic bromoacetamide moiety.
• Material Science Research: Employed in the creation of specialized monomers or cross-linking agents for advanced polymers with unique thermal or mechanical properties.
• Academic & Contract Research: A critical reagent for methodological development in organic synthesis, enabling novel cyclopropanation or ring-opening reactions.

Basic Information

Product Name	2-Bromo-n-Cyclopropyl-Acetamide
CAS No.	77600-79-4
Molecular Formula	C5H8BrNO
Molecular Weight	178.03 g/mol
Synonyms	2-Bromo-N-cyclopropylacetamide; N-Cyclopropyl-2-bromoacetamide; α-Bromo-N-cyclopropylacetamide; 2-Bromocyclopropylacetamide; Bromoacetic acid cyclopropylamide; Acetamide, 2-bromo-N-cyclopropyl-; (2-Bromoacetyl)cyclopropylamine
EINECS	Contact for details

Quality Control

Our 2-Bromo-n-Cyclopropyl-Acetamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically exceeding 97% (HPLC). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to cGMP principles where applicable, and our quality control protocols are designed to meet the stringent requirements of pharmaceutical and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.