Description

Sialyltransferase, Cytidine Monophosphoacetylneuraminate-.Beta.-Galactosyl(14)Acetylglucosaminide .Alpha.23- is a highly specialized glycosyltransferase enzyme critical for the biosynthesis of complex sialylated glycoconjugates. This compound serves as a key biochemical tool and intermediate for research and development in glycobiology and biopharmaceutical manufacturing. It is essential for scientists and process developers in the pharmaceutical, biotechnology, and diagnostic sectors who require precise enzymatic activity for synthesizing specific glycan structures.

Application

• Glycobiology Research: A fundamental reagent for in vitro studies of sialylation pathways, enzyme kinetics, and glycan biosynthesis mechanisms.
• Biopharmaceutical Development: Used in the enzymatic synthesis and remodeling of therapeutic glycoproteins, such as monoclonal antibodies, to optimize their biological activity and pharmacokinetic profiles.
• Diagnostic Reagent Production: Employed in the manufacture of enzymatic components for diagnostic kits that detect specific carbohydrate antigens or enzyme deficiencies.
• Synthetic Glycan Production: Acts as a catalyst for the chemoenzymatic synthesis of defined sialylated oligosaccharides and glycoconjugates for use as standards or probes.
• Cell Surface Engineering: Utilized to modify cell surface glycans for research in cell-cell recognition, signaling, and the development of cell-based therapies.

Basic Information

Product Name	Sialyltransferase, Cytidine Monophosphoacetylneuraminate-.Beta.-Galactosyl(14)Acetylglucosaminide .Alpha.23-
CAS No.	77537-85-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CMP-Neu5Ac-β-Gal-(1→4)-GlcNAc α-2,3-sialyltransferase; α-2,3-Sialyltransferase; ST3Gal; CMP-N-acetylneuraminate-β-galactosamide-α-(2→3)-sialyltransferase; Sialyltransferase 4A (ST4A); Glycoprotein sialyltransferase; EC 2.4.99.6 (related activity); CMP-Neu5Ac:β-D-Gal-(1→4)-D-GlcNAc α-2,3-sialyltransferase
EINECS	Contact for details

Quality Control

Our Sialyltransferase products undergo rigorous quality testing to ensure high purity, specific activity, and batch-to-batch consistency. Production and analysis follow stringent protocols suitable for research and development applications. Certificates of Analysis (COA) detailing parameters such as enzymatic activity, protein purity, and absence of contaminating activities are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms
Specific Activity	≥ [Value] U/mg
Protein Purity (SDS-PAGE)	≥ 90%
Endotoxin Level	< 1.0 EU/μg (if applicable)
Buffer Composition	Specified in COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.