Description

Adrenocorticotropic Hormone Rat CAS NO 77465-10-2 is a synthetic peptide fragment corresponding to the active sequence of rat adrenocorticotropic hormone (ACTH). This high-purity biochemical is essential for research into the hypothalamic-pituitary-adrenal (HPA) axis and stress response mechanisms. It is a critical reagent for pharmaceutical R&D, academic research, and diagnostic assay development in the life sciences sector.

Application

• Neuroscientific and Endocrine Research: Used to study the physiological effects of ACTH, including steroidogenesis, stress response, and behavioral models.
• Pharmaceutical Development: Serves as a reference standard and active pharmaceutical ingredient (API) intermediate in the development of therapeutics targeting adrenal disorders.
• Diagnostic Assay Manufacturing: Employed as a critical component (antigen/calibrator) in the production of immunoassays and ELISA kits for hormone level quantification.
• Biochemical Pathway Analysis: A key tool for investigating signal transduction pathways and receptor-ligand interactions involving melanocortin receptors.
• Veterinary Research: Applied in comparative endocrinology studies and the development of animal health products.

Basic Information

Product Name	Adrenocorticotropic Hormone Rat
CAS No.	77465-10-2
Molecular Formula	C₉₈H₁₄₈N₃₈O₃₁S
Molecular Weight	2463.8 g/mol
Synonyms	ACTH (rat); Adrenocorticotropin (rat); Corticotropin (rat); ACTH (1-24) (rat); CLIP (rat); Corticotropin-like intermediate lobe peptide (rat); Melanocyte-stimulating hormone release-inhibiting factor (rat); Synacthen (rat variant)
EINECS	Contact for details

Quality Control

Our Adrenocorticotropic Hormone Rat is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research-grade and cGMP standards for API intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.