Description

Dansyl α-Lactalbumin is a fluorescently labeled derivative of the milk protein α-lactalbumin, where the dansyl chloride moiety is covalently attached. This modification is crucial for enabling advanced spectroscopic studies, particularly in protein-protein interaction analysis and conformational change monitoring. It is an essential research-grade biochemical for scientists in biopharmaceutical development, nutritional science, and structural biology who require precise tracking of protein behavior under various experimental conditions.

Application

• Fluorescence Spectroscopy & Binding Studies: Used as a probe to investigate the binding interactions of α-lactalbumin with other proteins, peptides, or small molecules via fluorescence quenching or polarization assays.
• Protein Folding & Conformational Analysis: Serves as a sensitive reporter for monitoring unfolding, refolding, and structural transitions in α-lactalbumin under different denaturing conditions.
• Biomarker Research & Assay Development: Employed in the development of diagnostic or research assays where the specific detection of α-lactalbumin or its modified forms is required.
• Cell Biology & Microscopy: Can be utilized in cellular uptake studies or localization experiments, leveraging its fluorescent properties for visualization.
• Quality Control in Dairy & Infant Formula: Acts as a high-purity reference standard for analytical methods (e.g., HPLC, ELISA) aimed at quantifying α-lactalbumin content in food products.
• Academic & Industrial R&D: A fundamental tool for basic research on lactalbumin functionality and for applied research in developing functional foods or nutraceuticals.

Basic Information

Product Name	Dansyl α-Lactalbumin
CAS No.	77462-59-0
Molecular Formula	Contact for details
Molecular Weight	Approx. 14,200 Da (for protein moiety)
Synonyms	5-Dimethylaminonaphthalene-1-sulfonyl α-Lactalbumin; Dansyl-α-Lactalbumin; α-Lactalbumin, dansyl derivative; Lactalbumin, dansylated; LALBA-dansyl; Bovine α-Lactalbumin, Dansyl Labeled; Fluorescent α-Lactalbumin
EINECS	Contact for details

Quality Control

Our Dansyl α-Lactalbumin is produced and tested to meet stringent research-grade specifications. Each batch undergoes rigorous analysis to ensure high purity, correct labeling, and consistent fluorescent properties. Quality is verified through methods including HPLC, fluorescence spectroscopy, and SDS-PAGE. A comprehensive Certificate of Analysis (COA) detailing purity, degree of labeling, and performance data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	Light yellow to tan lyophilized powder
Identification (HPLC/FL)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	≥ 90%
Degree of Labeling (Molar Ratio)	0.8 - 1.2 mol Dansyl/mol protein
Fluorescence Emission Max	~500 nm (upon excitation at ~340 nm)
Solubility	Soluble in aqueous buffers (e.g., PBS, Tris)
Moisture Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.