Description

2-Amino-3-Fluoro-1-Phenylpropane is a fluorinated phenylpropylamine derivative, a versatile chiral building block of significant interest in advanced organic synthesis. Its core value lies in the strategic incorporation of fluorine and an amino group on the phenylpropane backbone, enabling precise modulation of biological activity and physicochemical properties in target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where enhanced metabolic stability or altered binding affinity is desired.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in constructing advanced intermediates for novel pesticides and herbicides, where the fluorine atom can improve lipophilicity and environmental stability.
• Chemical Biology & Proteomics: Serves as a building block for designing molecular probes and activity-based protein profiling (ABPP) agents to study enzyme function.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for asymmetric catalysis or metal complexes.
• Academic & Contract Research: Essential for methodological research in organic chemistry, particularly in studies involving fluorination and amine functionalization.
• Fine Chemical Production: Used in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	2-Amino-3-Fluoro-1-Phenylpropane
CAS No.	77449-02-6
Molecular Formula	C9H12FN
Molecular Weight	153.20 g/mol
Synonyms	1-Phenyl-2-amino-3-fluoropropane; 3-Fluoro-2-aminopropylbenzene; 2-Amino-3-fluoropropylbenzene; (RS)-2-Amino-3-fluoro-1-phenylpropane; (±)-2-Amino-3-fluoro-1-phenylpropane; 3-Fluoro-1-phenyl-2-propanamine; β-Fluoroamphetamine (structural analog); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Fluoro-1-Phenylpropane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.