Description

S-Mercuric-n-Dansylcysteine CAS NO 77430-00-3 is a specialized organomercury compound featuring a dansyl fluorophore, designed for advanced research and analytical applications. This reagent is critical for the selective labeling and detection of thiol groups in proteins and peptides, enabling high-sensitivity fluorescence-based assays. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and life science sectors for proteomics, enzyme studies, and biochemical analysis.

Application

• Fluorescent Labeling Agent: For the selective tagging of cysteine residues in proteins and peptides to facilitate detection and quantification.
• Proteomics Research: Used in the study of protein structure, function, and protein-protein interactions via fluorescence techniques.
• Biochemical Assay Development: Serves as a key component in developing sensitive assays for thiol-containing compounds.
• Enzyme Activity Studies: Employed to investigate enzymes with active-site cysteine residues through fluorescence quenching or enhancement.
• Pharmaceutical Analysis: Applied in the quality control of biopharmaceuticals to monitor disulfide bond formation and protein integrity.
• Diagnostic Reagent Manufacturing: Used in the production of specialized diagnostic kits and reagents for clinical research.

Basic Information

Product Name	S-Mercuric-n-Dansylcysteine
CAS No.	77430-00-3
Molecular Formula	C15H17HgN3O4S2
Molecular Weight	584.02 g/mol
Synonyms	5-Dimethylaminonaphthalene-1-sulfonylmercuric cysteine; Dansyl mercury cysteine; N-Dansyl-S-mercuric cysteine; S-(Dansylamidoethylmercuric)-L-cysteine; L-Cysteine, S-[2-[[(5-dimethylamino-1-naphthalenyl)sulfonyl]amino]ethylmercurio]-; Fluorescent mercury label; Thiol-specific fluorescent mercury probe
EINECS	Contact for details

Quality Control

Our S-Mercuric-n-Dansylcysteine is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, and specifications can be aligned with customer requirements for specific applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, the container should be kept in secondary opaque packaging or in a dark storage cabinet. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Mercury Content	Contact for details
Fluorescence Properties	Characteristic excitation/emission maxima
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.