Description

Argipressin, β-Mercapto Beta,β-Cyclopentamethylenepropionic Acid(1)-o-Methyl-Tyr(2)-Val(4)- is a synthetic analogue of the neurohypophysial hormone vasopressin, specifically designed with structural modifications to enhance its stability and receptor-binding profile. This compound is critical for advanced pharmaceutical research and development, particularly in the study of vasopressin receptor subtypes and their physiological roles. It serves as a key intermediate or active pharmaceutical ingredient (API) for researchers and manufacturers in the fields of endocrinology, cardiovascular research, and peptide-based therapeutics.

Application

• Pharmaceutical Research & Development: As a reference standard and key intermediate in the synthesis of novel vasopressin receptor agonists and antagonists.
• Biochemical Studies: For investigating the structure-activity relationships (SAR) of vasopressin and its interaction with V1a, V1b, and V2 receptors.
• Preclinical Development: Utilized in animal models to study conditions related to water balance, blood pressure regulation, and central nervous system functions.
• Peptide API Manufacturing: Serves as a building block or the final active ingredient in the production of specialized peptide therapeutics targeting hormonal disorders.
• Diagnostic Agent Development: Potential use in the development of diagnostic tools for disorders of the posterior pituitary gland.

Basic Information

Product Name	Argipressin, β-Mercapto Beta,β-Cyclopentamethylenepropionic Acid(1)-o-Methyl-Tyr(2)-Val(4)-
CAS No.	77403-97-5
Molecular Formula	C46H65N13O12S2
Molecular Weight	1040.2 g/mol
Synonyms	[1-(β-Mercapto-β,β-cyclopentamethylenepropionic acid), 2-(O-methyl-L-tyrosine), 4-L-valine]arginine vasopressin; [1-β-Mercapto-β,β-cyclopentamethylenepropionic acid, 2-O-methyltyrosine, 4-valine]Arg-vasopressin; d(CH2)5[Tyr(Me)2,Val4]AVP; Desmopressin analogue; V1a Vasopressin Receptor Antagonist; Manning Compound; β-Mercapto-β,β-cyclopentamethylenepropionyl1-O-methyl-Tyr2-Val4-Arg8-vasopressin
EINECS	Contact for details

Quality Control

Our Argipressin analogue is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development purposes. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While produced to meet high standards for research chemicals, specifications can be aligned with cGMP guidelines for advanced applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature between 15-25°C (59-77°F). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.