Description

β-Endorphin (Rat) is a synthetic peptide sequence identical to the endogenous neuropeptide found in rats, widely used as a critical research standard. This compound is essential for studying pain modulation, stress response, and reward pathways in preclinical rodent models. It is a fundamental tool for neuroscientists, pharmacologists, and biochemists in academic, pharmaceutical, and biotechnology research sectors. The product is supplied with a high level of purity and batch-to-batch consistency to ensure reliable and reproducible experimental results.

Application

• Neuroscience Research: Used as a reference standard in studies of opioid receptor binding, signal transduction, and neurochemical pathways.
• Pain and Analgesia Studies: Critical for investigating the mechanisms of endogenous pain relief and developing novel analgesic compounds.
• Behavioral Pharmacology: Applied in experiments examining stress, anxiety, depression, and reward-related behaviors in rodent models.
• Biochemical Assay Development: Serves as a calibrant and control in ELISA, RIA, and other immunoassay platforms for endorphin quantification.
• Cell Signaling Research: Used to stimulate cellular responses in vitro to study G-protein coupled receptor (GPCR) activity and downstream effects.
• Pharmaceutical R&D: Employed in the screening and validation of new drug candidates targeting the opioid system.

Basic Information

Product Name	β-Endorphin (Rat)
CAS No.	77367-63-6
Molecular Formula	C158H251N39O46S
Molecular Weight	3465.0 g/mol
Synonyms	β-Endorphin, rat; β-Endorphin (1-31), rat; Endorphin, β-, rat; Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu; C158H251N39O46S
EINECS	Contact for details

Quality Control

Our β-Endorphin (Rat) is manufactured under strict quality management protocols to ensure the highest standards for research use. Each batch is characterized by advanced analytical techniques including HPLC and mass spectrometry, with purity typically exceeding 95%. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and solvent residues is provided with every shipment to guarantee traceability and reproducibility for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. Aliquot into single-use vials to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by mass spectrometry
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.