Description

Ceftiolene CAS NO 77360-52-2 is a high-purity pharmaceutical intermediate belonging to the cephalosporin class of β-lactam antibiotics. This compound is critical for the synthesis of advanced antibiotic formulations, offering a reliable building block for research and production. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of novel antibacterial agents.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of advanced cephalosporin antibiotics.
• Antibacterial Research: Used in R&D laboratories for studying structure-activity relationships and developing new antibacterial compounds.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step manufacturing process of bulk antibiotic APIs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical analysis.

Basic Information

Product Name	Ceftiolene
CAS No.	77360-52-2
Molecular Formula	C20H20N6O7S2
Molecular Weight	520.54 g/mol
Synonyms	(6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; Ceftiolene; 7β-[2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]-3-cephem-4-carboxylic Acid; Antibiotic FR 17027; FR-17027
EINECS	Contact for details

Quality Control

Our Ceftiolene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade pharmaceutical intermediate specifications. Certificates of Analysis (COA) documenting full compliance are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.