Description

(S)-tert-Butyl (1,5-Diamino-1,5-Dioxopentan-2-Yl)Carbamate is a high-purity chiral building block and protected amino acid derivative essential for advanced organic synthesis. This compound matters because it serves as a critical intermediate for constructing complex peptide-based pharmaceuticals and bioactive molecules with precise stereochemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including protease inhibitors and other targeted drugs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Protease Inhibitor Development: Used in the research and production of inhibitors targeting specific enzymes like HIV protease or hepatitis C virus NS3/4A protease.
• Peptidomimetics Construction: Serves as a fundamental building block for creating peptidomimetics, which are molecules that mimic peptides but with enhanced stability and bioavailability.
• Solid-Phase Peptide Synthesis (SPPS): Employed in Fmoc/t-Bu SPPS strategies for the controlled incorporation of specific amino acid sequences.
• Bioconjugation and Labeling: Utilized in the preparation of modified peptides for diagnostic probes or targeted drug delivery systems.
• Chemical Biology Research: Acts as a tool compound for studying enzyme-substrate interactions and signal transduction pathways.

Basic Information

Product Name	(S)-tert-Butyl (1,5-Diamino-1,5-Dioxopentan-2-Yl)Carbamate
CAS No.	77345-20-1
Molecular Formula	C10H19N3O4
Molecular Weight	245.28 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)pentanediamide; (S)-2-((tert-Butoxycarbonyl)amino)glutaramic acid; (S)-Boc-DAP-OH; (S)-Boc-L-2,4-diaminobutyric acid derivative; (S)-N-Boc-2,4-diaminobutanoyl amide; (S)-tert-Butyl (1,5-diamino-1,5-dioxopentan-2-yl)carbamate; (S)-tert-Butyl 2-amino-4-carbamoylbutylcarbamate; Boc-Dap-NH2
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl (1,5-Diamino-1,5-Dioxopentan-2-Yl)Carbamate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and chiral purity analysis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.