Description

4-Nitro-2-Trifluoromethylacetophenone is a specialized aromatic ketone derivative, distinguished by its nitro and trifluoromethyl functional groups. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in fine chemical synthesis. It is primarily required by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those requiring a trifluoromethylated aromatic scaffold.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, leveraging the biological activity of the nitro and CF3 groups.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, reductions, and functional group transformations to create diverse chemical libraries.
• Material Science Research: Serves as a monomer or modifier in the development of specialty polymers and advanced organic materials.
• Chemical Research & Development: A valuable reagent for academic and industrial research exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	4-Nitro-2-Trifluoromethylacetophenone
CAS No.	77344-68-4
Molecular Formula	C9H6F3NO3
Molecular Weight	233.15 g/mol
Synonyms	1-(4-Nitro-2-(trifluoromethyl)phenyl)ethan-1-one; 2'-Trifluoromethyl-4'-nitroacetophenone; 4'-Nitro-2'-(trifluoromethyl)acetophenone; 4-Nitro-α,α,α-trifluoro-o-acetophenone; Ethanone, 1-[4-nitro-2-(trifluoromethyl)phenyl]-; 4-Nitro-2-trifluoromethyl acetophenone
EINECS	Contact for details

Quality Control

Our 4-Nitro-2-Trifluoromethylacetophenone is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.