Description

Benzonitrile, 4-Chloro-3-Methoxy-5-Nitro- is a high-purity, multi-functional aromatic nitrile derivative, serving as a critical advanced intermediate in fine chemical synthesis. Its unique substitution pattern makes it a valuable building block for constructing complex molecules with specific electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with nitro, chloro, and methoxy pharmacophores.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure.
• Dye & Pigment Manufacturing: Intermediate for producing specialized azo dyes and organic pigments where the nitro and cyano groups contribute to color fastness and molecular stability.
• Material Science Research: Used in the development of liquid crystals, organic semiconductors, and polymers requiring tailored electronic properties.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) for creating biaryl structures common in advanced materials.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating libraries of compounds for screening in various industries.

Basic Information

Product Name	Benzonitrile, 4-Chloro-3-Methoxy-5-Nitro-
CAS No.	77333-47-2
Molecular Formula	C8H5ClN2O3
Molecular Weight	212.59 g/mol
Synonyms	4-Chloro-3-methoxy-5-nitrobenzonitrile; 5-Nitro-4-chloro-3-methoxybenzonitrile; 2-Chloro-6-cyano-3-nitrophenyl methyl ether; 3-Methoxy-4-chloro-5-nitrobenzonitrile; Benzonitrile, 4-chloro-3-methoxy-5-nitro-; 4-Chloro-3-methoxy-5-nitro-benzonitrile
EINECS	Contact for details

Quality Control

Our Benzonitrile, 4-Chloro-3-Methoxy-5-Nitro- is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, impurities, and physical parameters is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.