Description

2'-n-Formimidoylistamycin B Disulfate Tetrahydrate is a chemically modified derivative of the lincosamide antibiotic lincomycin, characterized by the addition of a formimidoyl group. This compound is of significant interest in pharmaceutical research and development, particularly for the synthesis of novel antimicrobial agents and the study of structure-activity relationships. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in antibiotic discovery and advanced intermediate synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of novel lincosamide-class antibiotics.
• Antimicrobial Research: Used in biochemical and microbiological studies to investigate mechanisms of action and resistance against bacterial pathogens.
• Structure-Activity Relationship (SAR) Studies: A critical compound for modifying the lincomycin scaffold to enhance potency, spectrum of activity, or pharmacokinetic properties.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Process Chemistry Development: Used in scaling up and optimizing synthetic routes for the production of advanced antibiotic candidates.

Basic Information

Product Name	2'-n-Formimidoylistamycin B Disulfate Tetrahydrate
CAS No.	77312-56-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2'-N-Formimidoyllincomycin B Disulfate Tetrahydrate; Formimidoyllincomycin B Disulfate; Lincomycin B, 2'-N-formimidoyl-, disulfate, tetrahydrate; U-24729B; Antibiotic U-24729B; 2'-Deoxy-2'-[(formimidoyl)methylthio]lincomycin B Disulfate Tetrahydrate
EINECS	Contact for details

Quality Control

Our 2'-n-Formimidoylistamycin B Disulfate Tetrahydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC, to ensure it meets rigorous research-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	Consistent with tetrahydrate
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.