Description

Technetium Tc 99M N,N'-Bis(Mercaptoacetamido)Ethylenediamine is a critical bifunctional chelating agent used to radiolabel biomolecules for diagnostic imaging. This compound is essential for creating stable and specific radiopharmaceuticals used in Single Photon Emission Computed Tomography (SPECT). It is primarily needed by radiopharmaceutical manufacturers, nuclear medicine research facilities, and diagnostic imaging centers for developing targeted diagnostic agents.

Application

• Radiopharmaceutical Precursor: Primary agent for the preparation of Technetium-99m (99mTc) labeled diagnostic imaging agents.
• SPECT Imaging Tracers: Chelation core for developing tracers targeting specific receptors, enzymes, or cellular processes for non-invasive diagnosis.
• Biomolecule Conjugation: Used to attach the 99mTc radionuclide to peptides, antibodies, or other targeting vectors for tumor or inflammation imaging.
• Myocardial Perfusion Imaging: Key component in the synthesis of certain heart imaging agents to assess blood flow and cardiac function.
• Infection/Inflammation Imaging: Basis for agents used to localize sites of infection or inflammatory diseases.
• Research & Development: Vital tool in nuclear medicine research for developing novel diagnostic probes and studying biodistribution.
• Kit Formulation: Active pharmaceutical ingredient (API) in cold kits for the convenient, on-site preparation of 99mTc radiopharmaceuticals.

Basic Information

Item	Details
Product Name	Technetium Tc 99M N,N'-Bis(Mercaptoacetamido)Ethylenediamine
CAS No.	77275-80-0
Molecular Formula	C8H14N4O4S2
Molecular Weight	294.35 g/mol
Synonyms	N,N'-Ethylenebis[N-(mercaptoacetyl)glycine]; Ethylenedicysteine; EC; ECD (Ethyl Cysteinate Dimer precursor); L,L-ECD; Bicisate; Bicisate dihydrochloride precursor; HM-PAO related chelator; Diamide dimercaptide ligand
EINECS	Contact for details

Quality Control

Our Technetium Tc 99M N,N'-Bis(Mercaptoacetamido)Ethylenediamine is manufactured under strict quality systems suitable for radiopharmaceutical applications. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing results for assay, radiochemical purity, and specified impurities. Production adheres to current Good Manufacturing Practice (cGMP) principles where applicable to support our clients' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C) or as specified on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Radiochemical Purity	≥ 95.0% (upon labeling with 99mTc)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.