Description

N(3)-(Bromoacetyl)-2,3-Diaminopropanoic Acid is a specialized bifunctional amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its unique molecular architecture, featuring both a reactive bromoacetyl group and a diaminopropanoic acid backbone, enabling precise cross-linking and conjugation chemistries. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel peptide-based therapeutics, targeted drug delivery systems, and biochemical probes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex peptide-drug conjugates (PDCs) and antibody-drug conjugates (ADCs) for targeted cancer therapy.
• Bioconjugation Reagent: Used to create stable covalent linkages between peptides, proteins, and other biomolecules or synthetic payloads.
• Chemical Biology Research: Employed in the design and synthesis of activity-based probes (ABPs) and affinity labels for studying enzyme mechanisms.
• Cross-linking Agent: Facilitates the formation of intramolecular or intermolecular bridges in peptide and protein engineering to stabilize structures or create novel materials.
• Ligand Synthesis: Serves as a building block for creating chelating agents and ligands used in diagnostic imaging or metal-catalyzed reactions.

Basic Information

Product Name	N(3)-(Bromoacetyl)-2,3-Diaminopropanoic Acid
CAS No.	77215-58-8
Molecular Formula	C5H9BrN2O3
Molecular Weight	225.04 g/mol
Synonyms	2,3-Diaminopropanoic Acid, N3-(Bromoacetyl)-; 3-[(Bromoacetyl)amino]-2,3-diaminopropanoic Acid; (2R)-2,3-Diamino-3-oxopropyl bromoacetate (related ester); Bromoacetyl-Dap-OH; BrAc-DAP; L-2,3-Diaminopropionic Acid N3-Bromoacetyl Derivative; β-Bromoacetamido-L-α,β-diaminopropionic Acid
EINECS	Contact for details

Quality Control

Our N(3)-(Bromoacetyl)-2,3-Diaminopropanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring consistency and reliability for your research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.