Description

n-Methyl-n-(2-Hydroxyethyl)Tamoxifen is a chemically modified derivative of the well-known selective estrogen receptor modulator (SERM), Tamoxifen. This compound is of significant interest in pharmaceutical research and development, particularly for the synthesis of novel therapeutic agents targeting hormone-responsive conditions. It serves as a crucial intermediate for medicinal chemists and R&D laboratories focused on oncology, endocrinology, and advanced drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel Tamoxifen analogs and next-generation SERMs for research and development.
• Oncology Research: Used in preclinical studies to investigate structure-activity relationships (SAR) for anti-estrogenic and anti-cancer properties.
• Biochemical Research: Serves as a reference standard or probe compound in studies of estrogen receptor binding and modulation.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for chemical biology and medicinal chemistry projects.
• Process Development: Employed in the scale-up and optimization of synthetic routes for complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	n-Methyl-n-(2-Hydroxyethyl)Tamoxifen
CAS No.	77214-91-6
Molecular Formula	C26H29NO2
Molecular Weight	387.52 g/mol
Synonyms	N-Methyl-N-(2-hydroxyethyl)tamoxifen; 1-[4-[2-(Dimethylamino)ethoxy]phenyl]-1,2-diphenyl-1-buten-3-yl methyl(2-hydroxyethyl)amine; N-Methyl-N-(2-hydroxyethyl)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenyl-1-buten-3-amine; Tamoxifen N-methyl-N-(2-hydroxyethyl) derivative; Hydroxyethylmethyltamoxifen
EINECS	Contact for details

Quality Control

Our n-Methyl-n-(2-Hydroxyethyl)Tamoxifen is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.