Description

3-(2-Oxo-Pyrrolidin-1-Yl)-Propionic Acid is a versatile pyrrolidinone derivative with a propionic acid side chain, serving as a key intermediate in advanced organic synthesis. Its bifunctional structure makes it valuable for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific lactam and carboxylic acid functionalities.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the pyrrolidinone moiety can enhance biological activity.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored properties like adhesion or biocompatibility.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Bioconjugation and Linker Chemistry: The carboxylic acid group enables its use as a spacer or linker molecule in bioconjugation techniques for antibody-drug conjugates (ADCs) or diagnostic probes.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	3-(2-Oxo-Pyrrolidin-1-Yl)-Propionic Acid
CAS No.	77191-38-9
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	1-(2-Carboxyethyl)-2-pyrrolidinone; 2-Pyrrolidinone-1-propanoic Acid; 3-(2-Oxo-1-pyrrolidinyl)propanoic Acid; 1-(2-Carboxyethyl)pyrrolidin-2-one; N-(2-Carboxyethyl)-2-pyrrolidinone; γ-Butyrolactam-1-propionic Acid; 3-(2-Oxopyrrolidin-1-yl)propionic Acid
EINECS	Contact for details

Quality Control

Our 3-(2-Oxo-Pyrrolidin-1-Yl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.