Description

2-Propynoic Acid, 3-Iodo-, Ethyl Ester is a specialized halogenated alkyne ester, a high-value synthetic building block for advanced organic synthesis. Its core value lies in its dual functionality, offering both an electrophilic iodo group and an activated alkyne moiety for click chemistry and cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex molecules, particularly for introducing iodine or alkyne handles for further derivatization via Sonogashira or other palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the development of new crop protection agents and herbicides, where its reactive groups allow for the construction of diverse heterocyclic scaffolds.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with unique optical, electronic, or mechanical properties via click chemistry (e.g., CuAAC).
• Chemical Biology & Bioconjugation: Employed as a probe or linker for labeling biomolecules (proteins, nucleic acids) due to its reactivity in bioorthogonal reactions.
• Organic Synthesis Reagent: A versatile reagent for constructing C-C bonds and introducing iodine atoms into complex molecular architectures under mild conditions.

Basic Information

Product Name	2-Propynoic Acid, 3-Iodo-, Ethyl Ester
CAS No.	77190-24-0
Molecular Formula	C5H5IO2
Molecular Weight	223.99 g/mol
Synonyms	Ethyl 3-iodopropiolate; 3-Iodopropiolic Acid Ethyl Ester; Ethyl 3-Iodopropynoate; Iodopropiolic Acid Ethyl Ester; Propiolic Acid, 3-Iodo-, Ethyl Ester; 3-Iodo-2-propynoic Acid Ethyl Ester; Ethyl (3-Iodoprop-2-ynoate)
EINECS	Contact for details

Quality Control

Our 2-Propynoic Acid, 3-Iodo-, Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, handling and storage should minimize exposure to light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.