Description

Serine Racemase CAS NO 77114-08-0 is a specific enzyme inhibitor that plays a crucial role in modulating the D-serine pathway within the central nervous system. This compound is of significant interest for advanced biochemical research and pharmaceutical development due to its targeted mechanism of action. It is primarily utilized by research institutions and pharmaceutical companies focused on neuroscience, neuropharmacology, and the development of novel therapeutic agents for neurological disorders.

Application

• Neuroscience Research: A critical tool for studying the role of D-serine as an endogenous co-agonist of the NMDA receptor and its implications in synaptic plasticity, learning, and memory.
• Neuropharmacology Studies: Used to investigate pathological mechanisms and validate potential drug targets for conditions such as schizophrenia, stroke, neuropathic pain, and neurodegenerative diseases.
• Biochemical Pathway Analysis: Employed in in vitro and cellular assays to dissect the serine racemase enzymatic pathway and its regulation.
• High-Throughput Screening (HTS): Serves as a reference compound or positive control in HTS campaigns aimed at discovering new serine racemase modulators.
• Preclinical Drug Development: Used in animal models to evaluate the therapeutic potential and safety profile of modulating D-serine levels for various CNS indications.

Basic Information

Product Name	Serine Racemase
CAS No.	77114-08-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Serine Racemase Inhibitor; SR Inhibitor; D-Serine Synthesis Inhibitor; (S)-2-Amino-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carboxylic acid (common structural analog); Benzoxazine-based inhibitor; NMDA receptor co-agonist pathway modulator
EINECS	Contact for details

Quality Control

Our Serine Racemase is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot is characterized using advanced analytical techniques, including HPLC and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, potency, and analytical results is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Potency (Enzymatic Assay)	IC50 provided per batch
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.