Description

Msh, Des-Asp- CAS NO 77069-88-6 is a synthetic peptide derivative of α-melanocyte-stimulating hormone (α-MSH). This compound is of significant interest in biochemical and pharmaceutical research due to its role in studying melanocortin receptor pathways. It is primarily utilized by research institutions and pharmaceutical developers focused on endocrinology, dermatology, and metabolic disorders.

Application

• Biomedical Research: Used as a reference standard or active agent in studies of melanocortin receptors (MC1R, MC3R, MC4R, MC5R).
• Pharmacological Studies: Investigation of skin pigmentation, inflammation, and energy homeostasis mechanisms.
• Drug Discovery: Serves as a key intermediate or lead compound in the development of novel therapeutics for obesity, erectile dysfunction, and inflammatory conditions.
• In Vitro Diagnostics: Employed in assay development for receptor binding and activation studies.
• Academic Research: Fundamental research in peptide chemistry, hormone action, and signal transduction pathways.

Basic Information

Product Name	Msh, Des-Asp-
CAS No.	77069-88-6
Molecular Formula	C₇₇H₁₀₉N₂₁O₁₉S
Molecular Weight	1644.9 g/mol
Synonyms	Des-Asp-α-MSH; [Des-Asp5]-α-MSH; α-MSH (5-13); Melanotropin (5-13); Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂; N-Acetyl-α-MSH (5-13); Norleucine4, D-Phenylalanine7-α-MSH (4-10) (common fragment analog context)
EINECS	Contact for details

Quality Control

Our Msh, Des-Asp- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and impurity profiles are provided to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.