Description

Benzamide, n-(2-((((4-Chlorophenyl)Amino)Thioxomethyl)Amino)Cyclopenty L)-n-Methyl-4-Nitro- CAS NO 77051-92-4 is a specialized organic compound featuring a benzamide core integrated with thiourea and nitro-substituted aromatic functionalities. This complex molecular architecture makes it a valuable advanced intermediate for the synthesis of novel chemical entities, particularly in pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for constructing molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for compounds requiring a thiourea-linked aromatic system.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, or insecticides, leveraging its chlorophenyl and nitro group motifs common in crop protection agents.
• Chemical Biology Probe: Acts as a precursor for developing molecular probes to study enzyme inhibition or receptor binding, given its potential hydrogen-bonding capabilities from the thiourea and amide groups.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique thermal or mechanical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in client-directed synthesis projects requiring this specific molecular scaffold.

Basic Information

Product Name	Benzamide, n-(2-((((4-Chlorophenyl)Amino)Thioxomethyl)Amino)Cyclopenty L)-n-Methyl-4-Nitro- CAS NO 77051-92-4
CAS No.	77051-92-4
Molecular Formula	C20H21ClN4O3S
Molecular Weight	432.92 g/mol
Synonyms	N-(2-((((4-Chlorophenyl)amino)thioxomethyl)amino)cyclopentyl)-N-methyl-4-nitrobenzamide; 1-(2-((((4-Chlorophenyl)amino)thioxomethyl)amino)cyclopentyl)-1-methyl-3-(4-nitrobenzoyl)urea (tautomeric form); 4-Nitro-N-[2-[[(4-chlorophenyl)carbamothioyl]amino]cyclopentyl]-N-methylbenzamide; CAS 77051-92-4; Thiourea, N-[(2-[[(4-nitrophenyl)carbonyl](methyl)amino]cyclopentyl)carbamoyl]-N'-(4-chlorophenyl)-; Advanced Benzamide Thiourea Derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical properties are provided and available upon request. We support cGMP-compliant manufacturing for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.