Description

Almitrine-Raubasine is a well-defined pharmaceutical compound, a combination of almitrine and raubasine (also known as ajmalicine), with the CAS registry number 76997-30-3. This active pharmaceutical ingredient (API) is valued for its vasoactive properties and its role in the formulation of prescription medications. It is primarily sought by pharmaceutical manufacturers and research institutions engaged in the development and production of treatments for cerebrovascular and peripheral vascular disorders. The compound's specific pharmacological profile makes it a critical component in targeted therapeutic applications.

Application

• Pharmaceutical API: Primary use as the active ingredient in finished dosage forms, particularly oral tablets.
• Cerebrovascular Therapy: Formulation of medications indicated for the symptomatic treatment of chronic cerebrovascular insufficiency.
• Peripheral Vascular Disorders: Used in drugs targeting conditions like intermittent claudication and other circulatory issues.
• Clinical Research: Serves as a reference standard and key material in pharmacological studies and clinical trials.
• Generic Drug Manufacturing: Essential for companies producing generic versions of established almitrine-raubasine combination drugs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific production.

Basic Information

Product Name	Almitrine-Raubasine
CAS No.	76997-30-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Almitrine Mesylate and Raubasine; Almitrine and Ajmalicine; Duxil® (brand name mixture); Almitrine Raubasine Combination; Almitrine-Ajmalicine; 76997-30-3; Almitrine/Raubasine
EINECS	Contact for details

Quality Control

Our Almitrine-Raubasine is manufactured under strict quality systems suitable for pharmaceutical applications. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and strength. We provide full traceability and support regulatory filings with detailed documentation. Certificates of Analysis (COA) are available upon request, confirming compliance with in-house specifications and relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The original container should be resealed immediately after use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.