Description

Enkephalin-Leu, 4-(Hydroxyphenyl)Azo- is a chemically modified peptide derivative designed for advanced biochemical research and development. This compound is valued for its role as a specialized probe or intermediate in studying opioid receptor interactions and signal transduction pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on neuroscience, peptide chemistry, and diagnostic assay development.

Application

• Biochemical Research: Used as a specialized tool compound for investigating the structure-activity relationships (SAR) of enkephalin analogs and opioid receptors.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the synthesis and screening of novel peptide-based therapeutics targeting pain management.
• Diagnostic Reagents: Potential application in the development of enzyme-linked immunosorbent assays (ELISA) or other bioanalytical methods for detecting specific biological markers.
• Neuroscience Studies: Employed in vitro and ex vivo studies to probe neurotransmitter systems and cellular signaling mechanisms related to analgesia.
• Peptide Chemistry: Acts as a model compound for studying azo-dye conjugation techniques to peptides and the resulting photophysical or binding properties.

Basic Information

Product Name	Enkephalin-Leu, 4-(Hydroxyphenyl)Azo-
CAS No.	76995-91-0
Molecular Formula	C33H38N8O7
Molecular Weight	658.70 g/mol
Synonyms	4-(Hydroxyphenyl)azo-Leu-Enkephalin; Leu-Enkephalin, 4-(Hydroxyphenyl)azo derivative; [Leu5]-Enkephalin azo dye conjugate; Tyr-Gly-Gly-Phe-Leu-4-(hydroxyphenyl)azo; Azo-Leu-Enkephalin; Opioid peptide azo derivative; H-Tyr-Gly-Gly-Phe-Leu-NH-CH2-CH2-N=N-C6H4-OH (sequence notation)
EINECS	Contact for details

Quality Control

Our Enkephalin-Leu, 4-(Hydroxyphenyl)Azo- is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While not intended for human therapeutic use, its quality is managed with a focus on reliability and traceability for the research community.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Orange to red solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.