Description

10-Carboxydecylamino-Sepharose is a functionalized affinity chromatography medium designed for the selective purification of biomolecules. This product matters for its high ligand density and stable covalent linkage, enabling efficient capture and isolation of target proteins, antibodies, or enzymes. It is primarily needed by researchers and process development scientists in the biotechnology and pharmaceutical industries for downstream purification workflows.

Application

• Affinity Chromatography: For the purification of proteins, enzymes, or antibodies that bind specifically to the carboxydecyl functional group.
• Bioconjugate Research: As a solid support for immobilizing biomolecules to study protein-ligand interactions.
• Process Development: Scaling up purification processes in biopharmaceutical manufacturing.
• Sample Preparation: Pre-concentration and clean-up of specific analytes from complex biological mixtures prior to analysis.
• Enzyme Immobilization: Creating stable, reusable biocatalysts for industrial enzymatic reactions.
• Academic Research: A tool for biochemistry and molecular biology laboratories studying protein function and purification techniques.

Basic Information

Product Name	10-Carboxydecylamino-Sepharose
CAS No.	76929-94-7
Molecular Formula	Contact for details
Molecular Weight	N/A (Chromatography Medium)
Synonyms	10-Carboxydecylamino-Sepharose 4B; Sepharose 4B-(carboxymethyl)decylamine; N-(10-Carboxydecyl)amino-Sepharose; Carboxydecylamino-Sepharose CL-4B; CD-Sepharose; 10-Carboxydecyl-amino-Sepharose; 1-Carboxy-10-amino-decyl-Sepharose; Aminoalkyl-Sepharose derivative
EINECS	Contact for details

Quality Control

Our 10-Carboxydecylamino-Sepharose is produced under a quality management system. Each batch undergoes rigorous testing to ensure consistent performance, including assessment of ligand density, bead integrity, and binding capacity. Certificates of Analysis (COA) detailing lot-specific specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in the supplied storage solution (typically 20% ethanol). Do not freeze. The product is hygroscopic (moisture-sensitive); ensure the container is sealed properly after use to prevent drying or microbial contamination.

Specification

Item	Specification
Matrix	Sepharose 4B
Ligand	10-Carboxydecylamino
Ligand Density	10 - 20 μmol/mL gel (Typical)
Particle Size	45 - 165 μm
Maximum Flow Velocity	Contact for details
pH Stability (long term)	3 - 10
Storage Solution	20% Ethanol
Binding Capacity (for a model protein)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.